posaconazol
J - Antiinfectives For Systemic Use -> J02 - Antimycotics For Systemic Use -> J02A - Antimycotics For Systemic Use -> J02AC - Triazole Derivatives -> J02AC04 - Posaconazole
Administration category:
Free
Medicine group:
antifungal
Brand name:
Noxafil
Standard dosages
| Weight | ROA | Load | Dosage | |
|---|---|---|---|---|
|
ROA: po |
Load: 300mg |
Dosage: 300mg 1 dd |
||
|
ROA: po |
Load: - |
Dosage: 400mg 2 dd |
||
|
Comments:
po tabletten: dag 1 oplaad 300 mg 2 dd, dag 2 e.v. 300 mg 1 dd. po suspensie: 400 mg 2 dd (met voedsel), 200 mg 4 dd (zonder voedsel). Tabletten hebben de voorkeur boven suspensie. |
||||
| Weight | ROA | Load | Dosage | |
|---|---|---|---|---|
|
ROA: iv |
Load: 300mg |
Dosage: 300mg 1 dd |
||
|
Comments:
iv: dag 1 oplaad 300 mg 2 dd, dag 2 e.v. 300 mg 1 dd. |
||||
Kidney function
| ROA | GFR | Dosage | Interval | Comments |
|---|---|---|---|---|
| ROA: po | ||||
|
GFR: <50 |
Dosage: Geen dosisaanpassing nodig |
|||
| ROA: iv | ||||
|
GFR: <50 |
Dosage: Geen dosisaanpassing nodig |
|||
Renal elimination:
0%
Dosage:
independent on kidney function
Renal function-replacement therapy
CAPD: aanpassing van de dosering is niet noodzakelijk
Hemo dialysis: aanpassing van de dosering is niet noodzakelijk
CAV / VVHD: aanpassing van de dosering is niet noodzakelijk
Interactions
| Interaction with (ATC): | Expected effect: |
|---|---|
|
Interaction with (ATC): L04AD01 - Ciclosporin |
Expected effect: spiegel ciclosporine wordt hoger |
|
Interaction with (ATC): L04AD02 - Tacrolimus |
Expected effect: spiegel tacrolimus wordt hoger |
Pregnancy
Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16
For individual advice, consult an expert on site.
Metadata
Swab vid: M-500527.2
Updated: 09/12/2024 - 21:21
Status: Published
General comments
Spiegelcontrole (TDM) wenselijk.