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quinine

P - Antiparasitic Products, Insecticides And Repellents -> P01 - Antiprotozoals -> P01B - Antimalarials -> P01BC - Methanolquinolines -> P01BC01 - Quinine
Administration category: Free Medicine group: antiparasitic

Safety margins

≥ 18 years
Weight ROA Dosage
ROA:
po
Dosage:
to max. 600mg 3 dd
ROA:
iv
Dosage:
to max. 10mg/kg 3 dd
Comments:

oplaaddosis: kininedihydrochloride 20 mg/kg (max. 1800 mg), i.v. in 4 uur (goed gecontroleerd infuus). Gevolgd na 8 uur door 10 mg/kg (max 600 mg) 3dd

Kidney function

≥ 18 years
ROA GFR Dosage Interval Comments
ROA: po
GFR:
10 - 50
Dosage:
geen dosisaanpassing nodig
GFR:
<10
Dosage:
600 mg 1dd
ROA: iv
GFR:
10 - 50
Dosage:
geen dosisaanpassing nodig
GFR:
<10
Dosage:
Oplaaddosis: 20 mg/kg, max. 1800 mg, in 4 uur toedienen. Na 8 uur: 10 mg/kg, max 600 mg 1dd
Renal elimination: 5%
Dosage: dependent on kidney function

Renal function-replacement therapy

CAPD: po: 600 mg 1 dd. iv: oplaaddosis: 20 mg/kg, max. 1800 mg, in 4 uur toedienen. Na 8 uur: 10 mg/kg, max 600 mg 1dd

Hemo dialysis: po: 600 mg 1 dd. iv: oplaaddosis: 20 mg/kg, max. 1800 mg, in 4 uur toedienen. Na 8 uur: 10 mg/kg, max 600 mg 1dd

CAV / VVHD: po: 600 mg 2-3 dd. iv: oplaaddosis: 20 mg/kg, max. 1800 mg, in 4 uur toedienen. Na 8 uur: 10 mg/kg, max 600 mg 2-3dd

Pregnancy

Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:

For individual advice, consult an expert on site.
Metadata

Swab vid: M-500519.2
Updated: 09/21/2021 - 16:21
Status: Published

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