levofloxacine
J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01M - Quinolone Antibacterials -> J01MA - Fluoroquinolones -> J01MA12 - Levofloxacin
Administration category:
Free
Medicine group:
antibacterial
Brand name:
Tavanic
Safety margins
| Weight | ROA | Dosage |
|---|---|---|
|
ROA: po |
Dosage: min. 250mg 1 dd to max. 500mg 2 dd |
|
|
ROA: iv |
Dosage: min. 250mg 1 dd to max. 500mg 2 dd |
Kidney function
| ROA | GFR | Dosage | Interval | Comments |
|---|---|---|---|---|
| ROA: po | ||||
|
GFR: 20 - 50 |
Dosage: Normale aanvangsdosis 250-500 mg, vervolgens 125 - 250 mg 1-2 dd |
|||
|
GFR: 10 - 20 |
Dosage: Normale aanvangsdosis 250-500 mg, vervolgens 125 mg 1-2 dd |
|||
|
GFR: <10 |
Dosage: Normale aanvangsdosis 250-500 mg, vervolgens 125 mg 1 dd |
|||
| ROA: iv | ||||
|
GFR: 20 - 50 |
Dosage: Normale aanvangsdosis 250-500 mg, vervolgens 125 - 250 mg 1-2 dd |
|||
|
GFR: 10 - 20 |
Dosage: Normale aanvangsdosis 250-500 mg, vervolgens 125 mg 1-2 dd |
|||
|
GFR: <10 |
Dosage: Normale aanvangsdosis 250-500 mg, vervolgens 125 mg 1 dd |
|||
Renal elimination:
93%
Dosage:
dependent on kidney function
Renal function-replacement therapy
CAPD: Normale aanvangsdosis 250-500 mg, vervolgens 125 mg 1-2 dd
Hemo dialysis: Normale aanvangsdosis 250-500 mg, vervolgens 125 mg 1-2 dd
CAV / VVHD: Normale aanvangsdosis 250-500 mg, vervolgens 125 mg 1-2 dd
Interactions
| Interaction with (ATC): | Interaction with: | Expected effect: |
|---|---|---|
|
Interaction with (ATC): |
Interaction with: aluminium- en magnesiumzouten bevattende antacida |
Expected effect: vermindering absorptie levofloxacine |
|
Interaction with (ATC): |
Interaction with: ijzerzouten |
Expected effect: vermindering absorptie levofloxacine |
|
Interaction with (ATC): R03DA04 - Theophylline |
Interaction with: |
Expected effect: verhoging plasmaconcentratie theofylline |
Pregnancy
Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16
For individual advice, consult an expert on site.
Metadata
Swab vid: M-500518.1
Updated: 09/09/2021 - 17:04
Status: Published