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Home Medication antibacterial

ciprofloxacine

J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01M - Quinolone Antibacterials -> J01MA - Fluoroquinolones -> J01MA02 - Ciprofloxacin
Administration category: Free Medicine group: antibacterial Brand name: Ciproxin

Safety margins

≥ 18 years
Weight ROA Dosage
ROA:
 po 		Dosage:
 min. 250mg 2 dd to max. 750mg 2 dd
ROA:
 iv 		Dosage:
 min. 400mg 2 dd to max. 400mg 3 dd

Kidney function

≥ 18 years
ROA GFR Dosage Interval Comments
ROA: po
GFR:
 <30 		Dosage:
 250 - 750 mg 1dd
ROA: iv
GFR:
 <30 		Dosage:
 400 mg 1dd 		Comments:
 bij ernstig zieke patiënten overweeg: 400 mg 2dd

Notes GFR general:

Bij eenmalige toediening als profylaxe (van meningokokkose en bij gonorroe) is aanpassing van de dosering niet noodzakelijk.

Renal elimination: 40-70%
Dosage: dependent on kidney function

Renal function-replacement therapy

CAPD: Oraal: doseringsinterval verlengen 250 - 750 mg 1dd. Intraveneus: 400 mg 1dd, bij ernstig zieke patiënten overweeg 400 mg 2dd

Hemo dialysis: Oraal: doseringsinterval verlengen 250 - 750 mg 1dd. Intraveneus: 400 mg 1dd, bij ernstig zieke patiënten overweeg 400 mg 2dd

CAV / VVHD: Oraal: doseringsinterval verlengen 250 - 750 mg 1dd. Intraveneus: 400 mg 1dd, bij ernstig zieke patiënten overweeg 400 mg 2dd

Interactions

Interaction with (ATC): Interaction with: Expected effect:
Interaction with (ATC):
 R03DA04 - Theophylline 		Interaction with:
 		Expected effect:
 verhoging plasmaconcentratie theofylline
Interaction with (ATC):
 		Interaction with:
 ijzerzouten 		Expected effect:
 vermindering absorptie ciprofloxacine
Interaction with (ATC):
 		Interaction with:
 aluminium- of magnesium bevattende antacida 		Expected effect:
 vermindering absorptie ciprofloxacine
Interaction with (ATC):
 A02BX02 - Sucralfate 		Interaction with:
 		Expected effect:
 vermindering absorptie ciprofloxacine

Pregnancy

Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:

For individual advice, consult an expert on site.
Metadata

Swab vid: M-500491.1
Updated: 09/20/2021 - 14:12
Status: Published

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