valganciclovir
J - Antiinfectives For Systemic Use -> J05 - Antivirals For Systemic Use -> J05A - Direct Acting Antivirals -> J05AB - Nucleosides And Nucleotides Excl. Reverse Transcriptase Inhibitors -> J05AB14 - Valganciclovir
Administration category:
Free
Medicine group:
antiviral
Brand name:
Valcyte
Standard dosages
Weight | ROA | Load | Dosage | |
---|---|---|---|---|
ROA: po |
Load: 900mg |
Dosage: 900mg 2 dd |
||
Comments:
per os: dag 1 oplaaddosis 900 mg 2dd |
Kidney function
ROA | GFR | Dosage | Interval | Comments |
---|---|---|---|---|
ROA: po | ||||
Dosage: Inductiebehandeling: |
||||
GFR: 40 - 60 |
Dosage: Eerste gift 900 mg, gevolgd door 450 mg 2 dd |
|||
GFR: 25 - 40 |
Dosage: Eerste gift 900 mg, gevolgd door 450 mg 1 dd |
|||
GFR: 10 - 25 |
Dosage: Eerste gift 900 mg, gevolgd door 450 mg elke 2 dagen of 225 mg 1 dd |
|||
GFR: <10 |
Dosage: 450 mg 2 - 3x per week |
|||
Dosage: Onderhoudsbehandeling: |
||||
GFR: 40 - 60 |
Dosage: 450 mg 1 dd |
|||
GFR: 25 - 40 |
Dosage: 450 mg elke 2 dagen of 225 mg 1 dd |
|||
GFR: 10 - 25 |
Dosage: 450 mg 2x per week of 125 mg 1dd |
|||
GFR: <10 |
Dosage: 450 mg 1 - 2x per week |
Notes GFR general:
Overweeg dalspiegels bij onvoldoende effectiviteit of bijwerkingen.
Renal elimination:
90%
Dosage:
dependent on kidney function
Renal function-replacement therapy
CAPD: Inductiebehandeling: 450 mg 2-3x per week. Onderhoudsbehandeling: 450 mg 1-2x per week.
Hemo dialysis: Inductiebehandeling: eerste gift 900 mg, vervolgens 200 mg na elke dialyse. Onderhoudsbehandeling: 100 mg na elke dialyse.
CAV / VVHD: Inductiebehandeling: 450 mg om de dag of 225 mg 1dd. Onderhoudsbehandeling: 450 mg 2x per week of 125 mg 1dd.
Pregnancy
Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16
For individual advice, consult an expert on site.
Metadata
Swab vid: M-500455.1
Updated: 09/15/2021 - 12:24
Status: Published