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valganciclovir

J - Antiinfectives For Systemic Use -> J05 - Antivirals For Systemic Use -> J05A - Direct Acting Antivirals -> J05AB - Nucleosides And Nucleotides Excl. Reverse Transcriptase Inhibitors -> J05AB14 - Valganciclovir
Administration category: Free Medicine group: antiviral Brand name: Valcyte

Standard dosages

Weight ROA Load Dosage
ROA:
po
Load:
900mg
Dosage:
900mg 2 dd
Comments:

per os: dag 1 oplaaddosis 900 mg 2dd

Kidney function

≥ 18 years
ROA GFR Dosage Interval Comments
ROA: po
Dosage:
Inductiebehandeling:
GFR:
40 - 60
Dosage:
Eerste gift 900 mg, gevolgd door 450 mg 2 dd
GFR:
25 - 40
Dosage:
Eerste gift 900 mg, gevolgd door 450 mg 1 dd
GFR:
10 - 25
Dosage:
Eerste gift 900 mg, gevolgd door 450 mg elke 2 dagen of 225 mg 1 dd
GFR:
<10
Dosage:
450 mg 2 - 3x per week
Dosage:
Onderhoudsbehandeling:
GFR:
40 - 60
Dosage:
450 mg 1 dd
GFR:
25 - 40
Dosage:
450 mg elke 2 dagen of 225 mg 1 dd
GFR:
10 - 25
Dosage:
450 mg 2x per week of 125 mg 1dd
GFR:
<10
Dosage:
450 mg 1 - 2x per week

Notes GFR general:

Overweeg dalspiegels bij onvoldoende effectiviteit of bijwerkingen.
Renal elimination: 90%
Dosage: dependent on kidney function

Renal function-replacement therapy

CAPD: Inductiebehandeling: 450 mg 2-3x per week. Onderhoudsbehandeling: 450 mg 1-2x per week.

Hemo dialysis: Inductiebehandeling: eerste gift 900 mg, vervolgens 200 mg na elke dialyse. Onderhoudsbehandeling: 100 mg na elke dialyse.

CAV / VVHD: Inductiebehandeling: 450 mg om de dag of 225 mg 1dd. Onderhoudsbehandeling: 450 mg 2x per week of 125 mg 1dd.

Pregnancy

Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:

For individual advice, consult an expert on site.
Metadata

Swab vid: M-500455.1
Updated: 09/15/2021 - 12:24
Status: Published

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